diff --git a/Cargo.lock b/Cargo.lock
index 4795d02bdb..e723e73677 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -706,8 +706,11 @@ dependencies = [
  "common-error",
  "common-telemetry",
  "datanode",
+ "serde",
  "snafu",
+ "tempdir",
  "tokio",
+ "toml",
 ]
 
 [[package]]
@@ -4435,6 +4438,15 @@ dependencies = [
  "tracing",
 ]
 
+[[package]]
+name = "toml"
+version = "0.5.9"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "8d82e1a7758622a465f8cee077614c73484dac5b836c02ff6a40d5d1010324d7"
+dependencies = [
+ "serde",
+]
+
 [[package]]
 name = "tonic"
 version = "0.7.2"
diff --git a/README.md b/README.md
index d44fdb4a2e..adb34f5b81 100644
--- a/README.md
+++ b/README.md
@@ -53,3 +53,9 @@ OR
 // Start datanode with `log-dir` and `log-level` options.
 cargo run -- --log-dir=logs --log-level=debug datanode start
 ```
+
+Start datanode with config file:
+
+```
+cargo run -- --log-dir=logs --log-level=debug datanode start -c ./config/datanode.example.toml
+```
diff --git a/config/datanode.example.toml b/config/datanode.example.toml
new file mode 100644
index 0000000000..e1c435352f
--- /dev/null
+++ b/config/datanode.example.toml
@@ -0,0 +1,7 @@
+http_addr = '0.0.0.0:3000'
+rpc_addr = '0.0.0.0:3001'
+wal_dir = '/tmp/wal'
+
+[storage]
+type = 'File'
+data_dir = '/tmp/greptimedb/data/'
diff --git a/src/cmd/Cargo.toml b/src/cmd/Cargo.toml
index 974cbd9ecd..028f7e270a 100644
--- a/src/cmd/Cargo.toml
+++ b/src/cmd/Cargo.toml
@@ -14,3 +14,8 @@ common-telemetry = { path = "../common/telemetry", features = ["deadlock_detecti
 datanode = { path = "../datanode" }
 snafu = { version = "0.7", features = ["backtraces"] }
 tokio = { version = "1.18", features = ["full"] }
+toml = "0.5"
+
+[dev-dependencies]
+serde = "1.0"
+tempdir = "0.3"
diff --git a/src/cmd/src/datanode.rs b/src/cmd/src/datanode.rs
index 53a5dd678b..03c6a72e78 100644
--- a/src/cmd/src/datanode.rs
+++ b/src/cmd/src/datanode.rs
@@ -1,8 +1,10 @@
 use clap::Parser;
+use common_telemetry::logging;
 use datanode::datanode::{Datanode, DatanodeOptions};
 use snafu::ResultExt;
 
-use crate::error::{Result, StartDatanodeSnafu};
+use crate::error::{Error, Result, StartDatanodeSnafu};
+use crate::toml_loader;
 
 #[derive(Parser)]
 pub struct Command {
@@ -31,15 +33,23 @@ impl SubCommand {
 
 #[derive(Debug, Parser)]
 struct StartCommand {
-    #[clap(long, default_value = "0.0.0.0:3000")]
-    http_addr: String,
-    #[clap(long, default_value = "0.0.0.0:3001")]
-    rpc_addr: String,
+    #[clap(long)]
+    http_addr: Option<String>,
+    #[clap(long)]
+    rpc_addr: Option<String>,
+    #[clap(short, long)]
+    config_file: Option<String>,
 }
 
 impl StartCommand {
     async fn run(self) -> Result<()> {
-        Datanode::new(self.into())
+        logging::info!("Datanode start command: {:#?}", self);
+
+        let opts: DatanodeOptions = self.try_into()?;
+
+        logging::info!("Datanode options: {:#?}", opts);
+
+        Datanode::new(opts)
             .await
             .context(StartDatanodeSnafu)?
             .start()
@@ -48,12 +58,23 @@ impl StartCommand {
     }
 }
 
-impl From<StartCommand> for DatanodeOptions {
-    fn from(cmd: StartCommand) -> Self {
-        DatanodeOptions {
-            http_addr: cmd.http_addr,
-            rpc_addr: cmd.rpc_addr,
-            ..Default::default()
+impl TryFrom<StartCommand> for DatanodeOptions {
+    type Error = Error;
+    fn try_from(cmd: StartCommand) -> Result<Self> {
+        let mut opts: DatanodeOptions = if let Some(path) = cmd.config_file {
+            toml_loader::from_file!(&path)?
+        } else {
+            DatanodeOptions::default()
+        };
+
+        if let Some(addr) = cmd.http_addr {
+            opts.http_addr = addr;
         }
+
+        if let Some(addr) = cmd.rpc_addr {
+            opts.rpc_addr = addr;
+        }
+
+        Ok(opts)
     }
 }
diff --git a/src/cmd/src/error.rs b/src/cmd/src/error.rs
index 2cb414ebcf..cccbafc2f5 100644
--- a/src/cmd/src/error.rs
+++ b/src/cmd/src/error.rs
@@ -5,11 +5,20 @@ use common_error::prelude::*;
 #[derive(Debug, Snafu)]
 #[snafu(visibility(pub))]
 pub enum Error {
-    #[snafu(display("Fail to start datanode, source: {}", source))]
+    #[snafu(display("Failed to start datanode, source: {}", source))]
     StartDatanode {
         #[snafu(backtrace)]
         source: datanode::error::Error,
     },
+
+    #[snafu(display("Failed to read config file: {}, source: {}", path, source))]
+    ReadConfig {
+        source: std::io::Error,
+        path: String,
+    },
+
+    #[snafu(display("Failed to parse config, source: {}", source))]
+    ParseConfig { source: toml::de::Error },
 }
 
 pub type Result<T> = std::result::Result<T, Error>;
@@ -18,6 +27,7 @@ impl ErrorExt for Error {
     fn status_code(&self) -> StatusCode {
         match self {
             Error::StartDatanode { source } => source.status_code(),
+            Error::ReadConfig { .. } | Error::ParseConfig { .. } => StatusCode::InvalidArguments,
         }
     }
 
@@ -29,3 +39,23 @@ impl ErrorExt for Error {
         self
     }
 }
+
+#[cfg(test)]
+mod tests {
+    use super::*;
+
+    fn raise_read_config_error() -> std::result::Result<(), std::io::Error> {
+        Err(std::io::ErrorKind::NotFound.into())
+    }
+
+    #[test]
+    fn test_error() {
+        let e = raise_read_config_error()
+            .context(ReadConfigSnafu { path: "test" })
+            .err()
+            .unwrap();
+
+        assert!(e.backtrace_opt().is_none());
+        assert_eq!(e.status_code(), StatusCode::InvalidArguments);
+    }
+}
diff --git a/src/cmd/src/lib.rs b/src/cmd/src/lib.rs
index d9276f0f3c..192811c2e1 100644
--- a/src/cmd/src/lib.rs
+++ b/src/cmd/src/lib.rs
@@ -1,2 +1,3 @@
 pub mod datanode;
 pub mod error;
+mod toml_loader;
diff --git a/src/cmd/src/toml_loader.rs b/src/cmd/src/toml_loader.rs
new file mode 100644
index 0000000000..da87816e13
--- /dev/null
+++ b/src/cmd/src/toml_loader.rs
@@ -0,0 +1,54 @@
+macro_rules! from_file {
+    ($path: expr) => {
+        toml::from_str(
+            &std::fs::read_to_string($path)
+                .context(crate::error::ReadConfigSnafu { path: $path })?,
+        )
+        .context(crate::error::ParseConfigSnafu)
+    };
+}
+
+pub(crate) use from_file;
+
+#[cfg(test)]
+mod tests {
+    use std::fs::File;
+    use std::io::Write;
+
+    use serde::{Deserialize, Serialize};
+    use snafu::ResultExt;
+    use tempdir::TempDir;
+
+    use super::*;
+    use crate::error::Result;
+
+    #[derive(Clone, PartialEq, Debug, Deserialize, Serialize)]
+    struct MockConfig {
+        path: String,
+        port: u32,
+        host: String,
+    }
+
+    #[test]
+    fn test_from_file() -> Result<()> {
+        let config = MockConfig {
+            path: "/tmp".to_string(),
+            port: 999,
+            host: "greptime.test".to_string(),
+        };
+
+        let dir = TempDir::new("test_from_file").unwrap();
+        let test_file = format!("{}/test.toml", dir.path().to_str().unwrap());
+
+        let s = toml::to_string(&config).unwrap();
+        assert!(s.contains("host") && s.contains("path") && s.contains("port"));
+
+        let mut file = File::create(&test_file).unwrap();
+        file.write_all(s.as_bytes()).unwrap();
+
+        let loaded_config: MockConfig = from_file!(&test_file)?;
+        assert_eq!(loaded_config, config);
+
+        Ok(())
+    }
+}
diff --git a/src/datanode/src/datanode.rs b/src/datanode/src/datanode.rs
index b8c506c057..c7ba2fd74a 100644
--- a/src/datanode/src/datanode.rs
+++ b/src/datanode/src/datanode.rs
@@ -1,49 +1,40 @@
 use std::sync::Arc;
 
+use serde::{Deserialize, Serialize};
+
 use crate::error::Result;
 use crate::instance::{Instance, InstanceRef};
 use crate::server::Services;
 
-#[derive(Debug, Clone)]
-pub struct FileStoreConfig {
-    /// Storage path
-    pub store_dir: String,
-}
-
-impl Default for FileStoreConfig {
-    fn default() -> Self {
-        Self {
-            store_dir: "/tmp/greptimedb/data/".to_string(),
-        }
-    }
-}
-
-#[derive(Debug, Clone)]
+#[derive(Debug, Clone, Serialize, Deserialize)]
+#[serde(tag = "type")]
 pub enum ObjectStoreConfig {
-    File(FileStoreConfig),
+    File { data_dir: String },
 }
 
 impl Default for ObjectStoreConfig {
     fn default() -> Self {
-        ObjectStoreConfig::File(FileStoreConfig::default())
+        ObjectStoreConfig::File {
+            data_dir: "/tmp/greptimedb/data/".to_string(),
+        }
     }
 }
 
-#[derive(Clone, Debug)]
+#[derive(Clone, Debug, Serialize, Deserialize)]
 pub struct DatanodeOptions {
     pub http_addr: String,
     pub rpc_addr: String,
     pub wal_dir: String,
-    pub store_config: ObjectStoreConfig,
+    pub storage: ObjectStoreConfig,
 }
 
 impl Default for DatanodeOptions {
     fn default() -> Self {
         Self {
-            http_addr: Default::default(),
-            rpc_addr: Default::default(),
+            http_addr: "0.0.0.0:3000".to_string(),
+            rpc_addr: "0.0.0.0:3001".to_string(),
             wal_dir: "/tmp/wal".to_string(),
-            store_config: ObjectStoreConfig::default(),
+            storage: ObjectStoreConfig::default(),
         }
     }
 }
diff --git a/src/datanode/src/instance.rs b/src/datanode/src/instance.rs
index c5c605ba85..ac2fb37ad2 100644
--- a/src/datanode/src/instance.rs
+++ b/src/datanode/src/instance.rs
@@ -41,7 +41,7 @@ pub type InstanceRef = Arc<Instance>;
 
 impl Instance {
     pub async fn new(opts: &DatanodeOptions) -> Result<Self> {
-        let object_store = new_object_store(&opts.store_config).await?;
+        let object_store = new_object_store(&opts.storage).await?;
         let log_store = create_local_file_log_store(opts).await?;
 
         let table_engine = DefaultEngine::new(
@@ -177,20 +177,20 @@ impl Instance {
 
 async fn new_object_store(store_config: &ObjectStoreConfig) -> Result<ObjectStore> {
     // TODO(dennis): supports other backend
-    let store_dir = util::normalize_dir(match store_config {
-        ObjectStoreConfig::File(file) => &file.store_dir,
+    let data_dir = util::normalize_dir(match store_config {
+        ObjectStoreConfig::File { data_dir } => data_dir,
     });
 
-    fs::create_dir_all(path::Path::new(&store_dir))
-        .context(error::CreateDirSnafu { dir: &store_dir })?;
+    fs::create_dir_all(path::Path::new(&data_dir))
+        .context(error::CreateDirSnafu { dir: &data_dir })?;
 
-    info!("The storage directory is: {}", &store_dir);
+    info!("The storage directory is: {}", &data_dir);
 
     let accessor = Backend::build()
-        .root(&store_dir)
+        .root(&data_dir)
         .finish()
         .await
-        .context(error::InitBackendSnafu { dir: &store_dir })?;
+        .context(error::InitBackendSnafu { dir: &data_dir })?;
 
     Ok(ObjectStore::new(accessor))
 }
diff --git a/src/datanode/src/test_util.rs b/src/datanode/src/test_util.rs
index 6b3d1513d3..30ed650a9a 100644
--- a/src/datanode/src/test_util.rs
+++ b/src/datanode/src/test_util.rs
@@ -1,6 +1,6 @@
 use tempdir::TempDir;
 
-use crate::datanode::{DatanodeOptions, FileStoreConfig, ObjectStoreConfig};
+use crate::datanode::{DatanodeOptions, ObjectStoreConfig};
 
 /// Create a tmp dir(will be deleted once it goes out of scope.) and a default `DatanodeOptions`,
 /// Only for test.
@@ -16,9 +16,9 @@ pub fn create_tmp_dir_and_datanode_opts() -> (DatanodeOptions, TestGuard) {
     let data_tmp_dir = TempDir::new("/tmp/greptimedb_test_data").unwrap();
     let opts = DatanodeOptions {
         wal_dir: wal_tmp_dir.path().to_str().unwrap().to_string(),
-        store_config: ObjectStoreConfig::File(FileStoreConfig {
-            store_dir: data_tmp_dir.path().to_str().unwrap().to_string(),
-        }),
+        storage: ObjectStoreConfig::File {
+            data_dir: data_tmp_dir.path().to_str().unwrap().to_string(),
+        },
         ..Default::default()
     };