diff --git a/Dockerfile.compute-node b/Dockerfile.compute-node
index 299c4097e8..d91c7cfd72 100644
--- a/Dockerfile.compute-node
+++ b/Dockerfile.compute-node
@@ -520,8 +520,7 @@ RUN apt-get update && \
         libboost-regex1.74-dev \
         libboost-serialization1.74-dev \
         libboost-system1.74-dev \
-        libeigen3-dev \
-        libfreetype6-dev
+        libeigen3-dev
 
 ENV PATH "/usr/local/pgsql/bin/:/usr/local/pgsql/:$PATH"
 RUN wget https://github.com/rdkit/rdkit/archive/refs/tags/Release_2023_03_3.tar.gz -O rdkit.tar.gz && \
@@ -547,6 +546,7 @@ RUN wget https://github.com/rdkit/rdkit/archive/refs/tags/Release_2023_03_3.tar.
         -D PostgreSQL_LIBRARY_DIR=`pg_config --libdir` \
         -D RDK_INSTALL_INTREE=OFF \
         -D RDK_INSTALL_COMIC_FONTS=OFF \
+        -D RDK_BUILD_FREETYPE_SUPPORT=OFF \
         -D CMAKE_BUILD_TYPE=Release \
         . && \
     make -j $(getconf _NPROCESSORS_ONLN) && \
@@ -901,7 +901,7 @@ COPY --from=compute-tools --chown=postgres /home/nonroot/target/release-line-deb
 # libgeos, libgdal, libsfcgal1, libproj and libprotobuf-c1 for PostGIS
 # libxml2, libxslt1.1 for xml2
 # libzstd1 for zstd
-# libboost*, libfreetype6, and zlib1g for rdkit
+# libboost* for rdkit
 # ca-certificates for communicating with s3 by compute_ctl
 RUN apt update &&  \
     apt install --no-install-recommends -y \
@@ -914,7 +914,6 @@ RUN apt update &&  \
         libboost-serialization1.74.0 \
         libboost-system1.74.0 \
         libossp-uuid16 \
-        libfreetype6 \
         libgeos-c1v5 \
         libgdal28 \
         libproj19 \
@@ -926,7 +925,6 @@ RUN apt update &&  \
         libcurl4-openssl-dev \
         locales \
         procps \
-        zlib1g \
         ca-certificates && \
     rm -rf /var/lib/apt/lists/* /tmp/* /var/tmp/* && \
     localedef -i en_US -c -f UTF-8 -A /usr/share/locale/locale.alias en_US.UTF-8