diff --git a/test_runner/regress/test_download_extensions.py b/test_runner/regress/test_download_extensions.py
index c4bee1a1ea..b208616345 100644
--- a/test_runner/regress/test_download_extensions.py
+++ b/test_runner/regress/test_download_extensions.py
@@ -82,6 +82,7 @@ def upload_files(env):
 
 # Test downloading remote extension.
 @pytest.mark.parametrize("remote_storage_kind", available_s3_storages())
+@pytest.mark.skip(reason="https://github.com/neondatabase/neon/issues/4949")
 def test_remote_extensions(
     neon_env_builder: NeonEnvBuilder,
     remote_storage_kind: RemoteStorageKind,
@@ -148,6 +149,7 @@ def test_remote_extensions(
 
 # Test downloading remote library.
 @pytest.mark.parametrize("remote_storage_kind", available_s3_storages())
+@pytest.mark.skip(reason="https://github.com/neondatabase/neon/issues/4949")
 def test_remote_library(
     neon_env_builder: NeonEnvBuilder,
     remote_storage_kind: RemoteStorageKind,
@@ -205,10 +207,11 @@ def test_remote_library(
 # Here we test a complex extension
 # which has multiple extensions in one archive
 # using postgis as an example
-@pytest.mark.skipif(
-    RemoteStorageKind.REAL_S3 not in available_s3_storages(),
-    reason="skipping test because real s3 not enabled",
-)
+# @pytest.mark.skipif(
+#    RemoteStorageKind.REAL_S3 not in available_s3_storages(),
+#    reason="skipping test because real s3 not enabled",
+# )
+@pytest.mark.skip(reason="https://github.com/neondatabase/neon/issues/4949")
 def test_multiple_extensions_one_archive(
     neon_env_builder: NeonEnvBuilder,
     pg_version: PgVersion,
@@ -253,6 +256,7 @@ def test_multiple_extensions_one_archive(
 # Run the test with mutliple simultaneous connections to an endpoint.
 # to ensure that the extension is downloaded only once.
 #
+@pytest.mark.skip(reason="https://github.com/neondatabase/neon/issues/4949")
 def test_extension_download_after_restart(
     neon_env_builder: NeonEnvBuilder,
     pg_version: PgVersion,